Those who sat for about three hours a day were 33% less likely to die of cardiovascular disease than that for seven hours a day. Harvard Medical School followed more than 2,600 people ages 60 and older and recorded their typical sitting habits (including a weekday and weekend) for nine years.

This is because sitting causes blood to pool in your legs. If worse, it could lead to blood clots, which can cause deep vein thrombosis.

Findings from recent studies of Harvard Medical School have shown that more than 5,600 women followed for five years...

Boyle, Terry, et al. "Long-Term Sedentary Work and the Risk of Subsite-specific Colorectal Cancer".

As many as 70% of male office workers spend six or more hours each day sitting down.

The research found that the static seating position has been shown to lead to an increase in intradiscal pressure, which leads to disk bulges, protrusions, and, potentially, herniations

90% of men who sit for prolonged durations experienced erection dysfunction eventually.Sitting on a chair for hours at a stretch can increase the temperature inside the testes, thus destroying the sperm within it.

Every year around 2,500,000 Americans visit their doctor for constipation.

A gastroenterologist found that staying in a sitting position for long periods of time kinks up your colon, discouraging stool from passing through and causing constipation.